Details for gene set HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION[GSEA]

Table: GSEA Results Summary

Dataset	set03_truncNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION
Enrichment Score (ES)	0.7005445
Normalized Enrichment Score (NES)	2.0904822
Nominal p-value	0.0
FDR q-value	0.0015369914
FWER p-Value	0.0080

Fig 1: Enrichment plot: HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PKM2	3	15.094	0.1616	Yes
2	TPI1	9	12.552	0.2959	Yes
3	ALDOA	36	9.687	0.3983	Yes
4	PFKM	243	6.212	0.4538	Yes
5	PFKL	274	6.060	0.5172	Yes
6	PGAM1	344	5.641	0.5739	Yes
7	ENO1	585	4.674	0.6111	Yes
8	ENO3	648	4.480	0.6558	Yes
9	PGAM2	915	3.874	0.6830	Yes
10	PGK1	1248	3.300	0.7005	Yes
11	GNPDA1	2107	2.423	0.6804	No
12	GAPDHS	2969	1.939	0.6549	No
13	GNE	3207	1.836	0.6618	No
14	PFKP	5815	1.092	0.5333	No
15	ALDOC	7703	0.681	0.4391	No
16	PKLR	9147	0.367	0.3655	No
17	NPL	10691	-0.010	0.2826	No
18	GNPDA2	10967	-0.086	0.2687	No
19	ALDOB	11388	-0.201	0.2483	No
20	PGK2	15682	-2.085	0.0398	No
21	BPGM	17755	-5.300	-0.0149	No
22	ENO2	17890	-5.701	0.0390	No

Fig 2: HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION: Random ES distribution
Gene set null distribution of ES for HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION